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Test Code 273 Parathyroid Hormone (PTH), Intraoperative

Important Note

Human Anti-Mouse Antibodies (HAMA) may be present in samples from patients who have received immunotherapy utilizing monoclonal antibodies. Additionally, other heterophile antibodies such as human anti-goat antibodies may be present in patient samples. Manufacturers formulate assays to minimize the effects of these antibodies; however careful evaluation of patient results must be done when patients are known to have such antibodies.

Additional Codes

MLAB: PTHIO

PowerChart: Parathormone (PTH) Intact Intraoperative

Epic: LAB3245 PTH Intact Intra-OP

Test Method

Two-Site Immunoenzymatic ("Sandwich") Assay; Beckman

Specimen Requirement

0.5 mL heparin plasma is required.

Additional Specimen Collection Information

Collect blood in a lithium heparin, green-top. PST are not acceptable. Plasma should be separated from contact with the cells within 2 hours of collection. Specimens not centrifuged within 4 hours of collection may be rejected. Refrigerate the specimen if unable to assay within 8 hours of collection. Samples with ≥3+ lipemia must be cleared prior to analysis. All samples collected before and during the procedure must be collected from the same site peripheral to surgery. Typically this will be from an arterial line.

Performance

Testing is performed Monday through Sunday.

Typically completed within 30 minutes after the specimen arrives at the testing site.

Reference Values

12-88 pg/mL

50% or better reduction from baseline value.

CPT Code Information

83970: Chemistry: Parathormone (parathyroid hormone)

Useful For

Interoperative mode testing in patients under-going parathyroidectomy for primary hyperparathyroidism,

The following practices are recommended:

  • Baseline samples should be drawn at pre-operation/exploration and pre-excision.
  • Ordering pattern for the PTH-Intraoperative is typically baseline and then samples starting at about 10 minutes following resection and repeated until a 50% or better reduction from the baseline value is realized.           

 

LOINC Code Information

72203-3 Parathyrin.Intact Intraoperative Panel-Serum Or Plasma