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Test Code 274 Parathyroid Hormone (PTH), Intact with Minerals

Important Note

Human Anti-Mouse Antibodies (HAMA) may be present in samples from patients who have received immunotherapy utilizing monoclonal antibodies. Additionally, other heterophile antibodies such as human anti-goat antibodies may be present in patient samples. Manufacturers formulate assays to minimize the effects of these antibodies; however careful evaluation of patient results must be done when patients are known to have such antibodies.

Additional Codes

MLAB: PTHMIN

PowerChart: PTH Intact with Minerals

Epic: LAB2900 PTH with Minerals

Test Method

PTH: Two-Site Immunoenzymatic ("Sandwich") Assay; Beckman

Calcium: Ion Specific Electrode; Beckman

Phosphorus: Timed Endpoint Method; Beckman

Creatinine: Jaffe Rate; Beckman

GFR: Calculated

Specimen Requirement

0.5 mL serum or plasma is required.

Additional Specimen Collection Information

Collect blood in a lithium heparin, green-top, red-top. PST and SST (gel tubes) are acceptable.Serum or plasma should be separated from contact with the cells within 2 hours of collection. Specimens not centrifuged within 4 hours of collection may be rejected. Refrigerate the specimen if unable to assay within 8 hours of collection. Samples with ≥3+ lipemia must be cleared prior to analysis.

Performance

Testing is performed Monday through Sunday.

Typically completed the same day the specimen arrives at the testing site.

Reference Values

PTH: 12-88 pg/mL

Calcium: 8.5-10.5 mg/dL

  • Critical Values:
    • Low: < 6.0 mg/dL
    • High: > 13.0 mg/dL

Phosphorus: 2.0-4.5 mg/dL

Creatinine: 0.5-1.5 mg/dL

GFR:  60 mL/min/1.73m2

CPT Code Information

83970: Chemistry: Parathormone (parathyroid hormone)

82310: Chemistry: Calcium, total

84100: Chemistry: Phosphorus inorganic (phosphate)

82565: Chemistry: Creatinine; blood

Useful For

Diagnosis and differential diagnosis of hypercalcemia

Diagnosis of primary, secondary, and tertiary hyperparathyroidism

Diagnosis of hypoparathyroidism

Monitoring end-stage renal failure patients for possible renal osteodystrophy

LOINC Code Information

2731-8 Parathyrin.Intact [Mass/Volume] In Serum Or Plasma