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Test Code APCRV Activated Protein C Resistance V (APCRV), Plasma

Additional Codes

MLAB: Y8W

Powerchart: Protein C Resistance

Epic: LAB2265 Activated Protein C Resistance

MA Cerner: Activated Protein C Resistance V.

Reporting Name

Activated Protein Resistance V, P

Useful For

Evaluation of patients with incident or recurrent venous thromboembolism (VTE)

 

Evaluation of individuals with a family history of VTE

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Plasma Na Cit


Specimen Required


See Coagulation Studies in Special Instructions.

 

Specimen Type: Platelet-poor plasma

Collection Container/Tube: Light-blue top (citrate)

Submission Container/Tube: Polypropylene vial

Specimen Volume: 1 mL

Collection Instructions:

1. Spin down, remove plasma

2. Spin plasma again; remove plasma aliquot without disturbing bottom 0.5 mL

3. Freeze specimen aliquot immediately at or below -40 degrees C, if possible but no longer than 4 hours after collection

Additional Information:

1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

2. If priority specimen, mark request form, give reason, and request a call-back.

3. Each coagulation assay requested should have its own vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen 14 days

Special Instructions

Reference Values

APCRV RATIO

≥2.3

Pediatric reference range has neither been established nor is available in scientific literature. The adult reference range likely would be applicable to children older than 6 months.

Day(s) and Time(s) Performed

Monday through Friday

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

85307

LOINC Code Information

Test ID Test Order Name Order LOINC Value
APCRV Activated Protein Resistance V, P 13590-5

 

Result ID Test Result Name Result LOINC Value
APCR APCRV Ratio 13590-5
INT55 Interpretation 48591-2

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

Mild OK; Gross reject

Other

NA

Method Name

Clot-Based Assay

Forms

If not ordering electronically, complete, print, and send a Coagulation Test Request Form (T753) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/coagulation-test-request-form.pdf)