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Test Code EMA Endomysial Antibodies (IgA), Serum

Additional Codes

MLAB: Y4E

Powerchart: Endomysial IgA Autoantibody

Epic: LAB4429 Endomysial Ab IgA

MA Cerner: Endomysial Antibodies (IgA).

Reporting Name

Endomysial Abs, S (IgA)

Useful For

Diagnosis of dermatitis herpetiformis and celiac disease

 

Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease

 

Because of the high specificity of endomysial antibodies for celiac disease, the test may obviate the need for multiple small bowel biopsies to verify the diagnosis. This may be particularly advantageous in the pediatric population, including the evaluation of children with failure to thrive.

Testing Algorithm

If EMA / Endomysial Antibodies (IgA), Serum is positive or indeterminate, EMAT / Endomysial (IgA), Titer, Serum will be performed at an additional charge.

 

The following algorithms are available in Special Instructions:

-Celiac Disease Comprehensive Cascade

-Celiac Disease Diagnostic Testing Algorithm

-Celiac Disease Gluten-Free Cascade

-Celiac Disease Routine Treatment Monitoring Algorithm

-Celiac Disease Serology Cascade

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Container/Tube: 

Preferred: Serum gel

Acceptable: Red Top

Specimen Volume: 2 mL


Specimen Minimum Volume

Adults: 1 mL/Pediatric: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  14 days

Reference Values

Negative in normal individuals; also negative in dermatitis herpetiformis or celiac disease patients adhering to gluten-free diet. See Results of IF Testing in Cutaneous Immunofluorescence Testing in Special Instructions.

Day(s) and Time(s) Performed

Monday through Friday; 7 a.m.-5 p.m.

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86255-screen

86256-titer (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EMA Endomysial Abs, S (IgA) 27038-9

 

Result ID Test Result Name Result LOINC Value
9360 Endomysial Ab 27038-9

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild reject; Gross reject

Icterus

Mild OK; Gross reject

Other

NA

Method Name

Staining of Rhesus Monkey Esophagus Substrate by Indirect Immunofluorescence Assay (IFA) for IgA Endomysial Antibodies (EMA)

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
EMAT EMA Titer, S (IgA) No No