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Test Code HEPTP Heparin Anti-Xa, Plasma

Additional Codes

MLAB: Y5X
Powerchart: Heparin Anti Xa Assay
Epic: LAB2513 Heparin Anti Xa Assay
MA Cerner: Heparin Anti Xa Assay.

Secondary ID

40938

Useful For

Measuring heparin concentration:

-In patients treated with low-molecular-weight heparin preparations

-In the presence of prolonged baseline activated partial thromboplastin time (APTT) (eg, lupus anticoagulant, "contact factor" deficiency, etc)

-When unfractionated heparin dose needed to achieve desired APTT prolongation is unexpectedly higher (>50%) than expected

 

Not useful for monitoring therapy with the heparinoid "danaparoid"

Method Name

Chromogenic Method

Reporting Name

Heparin Anti-Xa, P

Specimen Type

Plasma Na Cit


Specimen Required


Specimen Type: Platelet-poor plasma

Collection Container/Tube: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Spin down, remove plasma and spin plasma again

Additional Information: Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen (preferred) 14 days
  Ambient  2 hours

Reject Due To

Hemolysis

Mild OK; Gross Reject

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross OK

Other

NA

Reference Values

Adult Therapeutic Range

UFH therapeutic range: 0.30-0.70 IU/mL

(6 hours following initiation or dose adjustment)

LMWH therapeutic range: 0.50-1.00 IU/mL for twice daily dosing*

LMWH therapeutic range: 1.00-2.00 IU/mL for once daily dosing*

LMWH prophylactic range: 0.10-0.30 IU/mL

(*sample obtained 4-6 hours following subcutaneous injection)

 

Heparin Anti-Xa assay is used to measure heparin concentrations in patients receiving low-molecular-weight heparin or unfractionated heparin.

Day(s) and Time(s) Performed

Monday through Sunday; Continuously

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

85520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HEPTP Heparin Anti-Xa, P In Process

 

Result ID Test Result Name Result LOINC Value
HEPTP Heparin Anti-Xa, P In Process