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Test Code REPU Electrophoresis, Protein, Random, Urine

Additional Codes

MLAB: YJU

Powerchart: Protein Electrophoresis Random Urine

Epic: LAB3514 Protein ELP, Random U

Reporting Name

Electrophoresis, Protein, Random, U

Useful For

Identifying monoclonal gammopathies using random urine specimens

Profile Information

Test ID Reporting Name Available Separately Always Performed
RPEU Protein Electrophoresis, Random, U No Yes
PTCON Protein, Total, Random, U No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
RIFXU Immunofixation, Random, U No No

Testing Algorithm

Urine protein electrophoresis alone is not considered an adequate screening for monoclonal gammopathies. If a discrete electrophoresis band is identified, the laboratory will evaluate the urine protein electrophoresis and, if necessary, perform immunofixation at an additional charge.

 

The following algorithms are available in Special Instructions:

-Laboratory Approach to the Diagnosis of Amyloidosis

-Laboratory Screening Tests for Suspected Multiple Myeloma

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Urine


Advisory Information


Random urine specimens may be sufficient for identifying monoclonal proteins, but 24-hour specimens should be used to quantitate and monitor urinary abnormalities. See MPSU / Monoclonal Protein Study, 24 Hour, Urine.



Shipping Instructions


Refrigerate specimen during collection and send refrigerated.



Necessary Information


Random urine, no volume is required.



Specimen Required


Supplies: Aliquot Tube, 5 mL (T465)

Submission Container/Tube: Plastic, 60-mL urine bottle and plastic, 5-mL tube (T465)

Specimen Volume: 50 mL

Collection Instructions:

1. Collect a random urine specimen.

2. Aliquot specimen between containers.

4. Label specimens appropriately (60-mL urine bottle for protein electrophoresis and 5-mL tube for protein, total).


Specimen Minimum Volume

25 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  5 days
  Ambient  72 hours

Reference Values

PROTEIN, TOTAL

No reference values apply to random urine.

 

ELECTROPHORESIS, PROTEIN

The following fractions, if present, will be reported as a percent of the total protein:

Albumin

Alpha-1-globulin

Alpha-2-globulin

Beta-globulin

Gamma-globulin 

No reference values apply to random urines.

Day(s) and Time(s) Performed

Total Protein: Monday through Sunday; Continuous

Protein Electrophoresis: Monday through Saturday; 12 p.m.

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84156-Protein, total

84166-Electrophoresis, protein

86335-Immunofixation (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
REPU Electrophoresis, Protein, Random, U In Process

 

Result ID Test Result Name Result LOINC Value
33039 Albumin 13992-3
33040 Alpha 1-Globulin 13990-7
33041 Alpha 2-Globulin 13993-1
33042 Beta-Globulin 13994-9
33043 Gamma-Globulin 13995-6
33044 A/G Ratio 44293-9
33045 M spike 42483-8
33046 M spike 42483-8
33047 Impression 49299-1
PTCON Protein, Total, Random, U 2888-6

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

NA

 

Method Name

PTCON: Turbidimetry

RPEU: Agarose Gel Electrophoresis

RIFXU: Immunofixation

Secondary ID

60068

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

 

Ambient

Yes

Refrigerated

Preferred

Frozen

Yes

6N HCl

No

50% Acetic Acid

No

Na2CO3

No

Toluene

Yes

6N HNO3

No

Boric Acid

No

Thymol

Yes