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Test Code VZG Varicella zoster Antibody, IgG, Serum

Important Note

The performance of this test has not been established for use in neonates, immunosuppressed or organ transplant individuals.

Additional Codes

MLAB: VZG
Powerchart: Varicella Zoster Antibody Screen
Epic: LAB162 Varicella Zoster Antibody, IgG
MA Cerner: Varicella Antibody, IgG, Serum

Test Method

Multiplex Flow Immunoassay; BioRad BioPlex

Specimen Requirement

Serum, EDTA or heparinized plasma are also acceptable. Gel tubes are acceptable.

Additional Specimen Collection Information

Collect blood in a serum or plasma gel tube (EDTA or heparin).

  • Minimum volume: 500 mcL
  • Hemolysis: > 2+ not acceptable
  • Lipemia > 3+ must be ultracentrifuged
  • Icterus: no significant interference noted
  • Storage: specimen is stable for up to 7 days refrigerated; freeze at -20oC for long term storage.
    Thoroughly mix thawed specimens; it is also recommended to centrifuge thawed specimens to remove gross particulate matter. Avoid multiple freeze-thaw cycles (up to 3 cycles are acceptable).

Performance

Testing is performed Monday through Sunday.
Routine: Typically completed within 4 hours after the specimen arrives at the testing site.

Reference Values

Varicella zoster: Positive (≥1.1 AI)
Positive: The presence of antibody suggests immunization or past or current infection.

CPT Code Information

86787 Antibody; Varicella-zoster, IgG

Useful For

Determination of immune status of individuals to the varicella-zoster virus (VZV).
Documentation of previous infection with VZV in an individual without a previous record of immunization to VZV.

LOINC Code Information

15410-4 Varicella zoster virus IgG Ab [Presence] in Serum by Immunoassay