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Test Code MMRVG MMRV Immune Status Profile, Serum

Important Note

The performance of this test has not been established for use in a pediatric population, neonates and immunocompromised patients.

Additional Codes


Powerchart: Measles, Mumps, Rubella, Varicella Ab Panel

Epic: MMRV Panel  [LAB5135]

MA Cerner: MMRV Immune Status Profile, Serum

Test Method

Multiplex Flow Immunoassay; BioRad BioPlex

Specimen Requirement

Serum is preferred, EDTA or heparinized plasma are also acceptable. Gel tubes are acceptable.

Additional Specimen Collection Information

Collect blood in a serum or plasma gel tube (EDTA or heparin).

  • Minimum volume: 500 mcL
  • Hemolysis: > 2+ not acceptable
  • Lipemia: > 3+ must be ultracentrifuged
  • Icterus: no significant interference noted
  • Storage: specimen is stable for up to 7 days refrigerated; freeze at -20oC for long term storage.
    Thoroughly mix thawed specimens; it is also recommended to centrifuge thawed specimens to remove gross particulate matter. Avoid multiple freeze-thaw cycles (up to 3 cycles are acceptable).


Testing is performed Monday through Sunday.
Routine: Typically completed within 4 hours after the specimen arrives at the testing site.

Reference Value

Positive: The presence of antibody suggests immunization or past or current infection

  • Measles: Positive (≥1.1 AI)
  • Mumps: Positive (≥1.1 AI)
  • Rubella: Positive (≥10 AIU/mL)
  • Varicella zoster: Positive (≥1.1 AI)


CPT Code Information

86735 Antibody; Mumps virus, IgG
86762 Antibody; Rubella, IgG
86765 Antibody; Rubeola, IgG
86787 Antibody; Varicella-zoster, IgG

Useful For

  • Determination of immune status of individuals to measles, mumps, rubella, and varicella-zoster viruses (VZV)
  • Documentation of previous infection with measles, mumps, rubella, or VZV in an individual without a previous record of immunization to these viruses

LOINC Code Information

15410-4 Varicella zoster virus IgG Ab [Presence] in Serum by Immunoassay
40667-8 Rubella virus IgG Ab [Presence] in Serum by Immunoassay
6476-6 Mumps virus IgG Ab [Presence] in Serum by Immunoassay
35275-7 Measles virus IgG Ab [Presence] in Serum by Immunoassay